Recommendations for Clinical Molecular Laboratories for Detection of Homologous Recombination Deficiency in Cancer A Joint Consensus Recommendation of the Association for Molecular Pathology, Association of Cancer Care Centers, and College of American Pathologists
This course contains the webinar, a handout, and continuing education credit (CME and CMLE)
Description:
This webinar will review the recently published expert consensus recommendations for clinical molecular laboratories for the detection of homologous recombination deficiency (HRD) in cancer, developed by the AMP Clinical Practice Committee’s PARP HRD Working Group. With representation from the Association of Cancer Care Centers, American Society of Clinical Oncology, and College of American Pathologists, the Working Group developed these recommendations, informed by the findings from a scoping literature review, laboratory practice survey, stakeholder input, and the cumulative practice experience of the members. The recommendations encompass pre-analytical, analytical, and postanalytical factors that play a role in genomic instability and/or HRD analytical validation and reporting.
Learning Objectives:
- Identify challenges in detecting and reporting homologous recombination deficiency.
- Discuss recommendations for clinical HRD assay validation, testing, and reporting.
Speaker
Susan Hsiao, MD, PhD
Columbia University
Moderator
Susan Harley, MD
University of Arkansas for Medical Sciences
Duration: 1 Hour
Level of Instruction: Basic
Broadcast Date: March 5, 2026
Date Recorded: October 31, 2025
Planned and coordinated by the Clinical Practice Committee and Training and Education Committee
Continuing Education Credit Information
CME credit: 1.0
CMLE credit: 1.0
Last day to claim credit: March 20, 2029
Accreditation Statements
AMA PRA Category 1 Credit(s)™
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint providership of American Society for Clinical Pathology (ASCP) and Association for Molecular Pathology (AMP). The American Society for Clinical Pathology (ASCP) is accredited by the ACCME to provide continuing medical education for physicians.
The ASCP designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.
CMLE
This continuing medical laboratory education activity is recognized by the American Society for Clinical Pathology for 1.0 hours of CMLE credit. ASCP CMLE credit hours are acceptable for the ASCP Board of Certification (BOC) Certification Maintenance Program (CMP). CMLE credit hours meet the continuing education requirements for the ASCP Board of Certification Credential Maintenance Program (CMP) and state relicensure requirements for laboratory personnel. Participants should claim only the credit commensurate with the extent of their participation in the activity.
Note: Members of AMP can access this webinar at no cost. Join the AMP Family!
All sales are final. No refunds will be issued.
No digital files may be reproduced or transmitted in any form, by any means, electronic or mechanical. By purchasing a product, you agree to not share any of the course materials, including videos, downloadable slide presentations, outlines, manuscripts, etc. without explicit and written permission from AMP.
