Molecular Subtypes of Diffuse Large B-cell Lymphoma
Description:
This presentation will outline molecular subtypes of diffuse large B-cell lymphoma (DLBCL), including those recognized by the latest classifications and those that are emerging and close to the clinic. The subtypes will be described, along with their clinical relevance and the challenges to implement appropriate assays in the laboratory. Finally, the evolution of DLBCL from diagnosis to relapse will be outlined with implications for molecular testing and our understanding of disease biology and patient management.
Learning Objectives:
- Recognize the
molecular subtypes of DLBCL within the WHO HAEM5 and ICC classifications and
describe the key differences between these schema.
- Understand the
origin and biology of the recently described dark zone lymphomas.
- Illustrate the challenges of implementing
appropriate assays for assigning genetic subtypes of DLBCL.
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| Speaker: David W Scott; MBChB,
PhD |
Moderator: Jennifer Bynum, MD Northside Hospital and Laboratories |
Level of Instruction: Intermediate
Date Recorded: August 3, 2023
Planned and coordinated by the Training and Education Committee
Continuing Education Credit Information
CME credit: 1.0CMLE credit: 1.0
Last day to claim credit: March 20, 2026
Accreditation Statements
AMA PRA Category 1 Credit(s)™
This
activity has been planned and implemented in accordance with the
Essential Areas and policies of the Accreditation Council for Continuing
Medical Education through the joint providership of American Society
for Clinical Pathology (ASCP) and Association for Molecular Pathology
(AMP). The American Society for Clinical Pathology (ASCP) is accredited
by the ACCME to provide continuing medical education for physicians.
The ASCP designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.
CMLE
This continuing medical laboratory education activity is recognized by the American Society for Clinical Pathology for 1.0 hours
of CMLE credit. ASCP CMLE credit hours are acceptable for the ASCP
Board of Certification (BOC) Certification Maintenance Program
(CMP). CMLE credit hours meet the continuing education requirements for
the ASCP Board of Certification Credential Maintenance Program (CMP) and
state relicensure requirements for laboratory personnel. Participants
should claim only the credit commensurate with the extent of their
participation in the activity.
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