AMP Horizons Series : Using Machine Learning to Improve Variant Reporting

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SKU:
311HZN19-004

Please note that this content was created in 2019. In the time since this material was posted, there may have been additional developments, advancements, and/or more current publications in this field.

AMP Education is constantly updating our educational offerings, and will remove or replace content that is no longer accurate. Please be sure to use the search function to find related or updated material available in our catalogue at educate.amp.org. The Training and Education Committee works with AMP Education Programs to bring you the most up-to-date and cutting-edge information on molecular pathology research, applications, and training.


Description: 

Next-generation sequencing technologies are actively applied in clinical oncology. Bioinformatics pipeline analysis is an integral part of this process; however, humans cannot yet realize the full potential of the highly complex output and the decision to include a variant in the final report remains challenging.  Machine learning is one approach to mine big data and derive models for decision-making.  Given that bioinformatics pipelines generate mostly structured, discrete data, the setting is ideal to assess a machine learning decision support system.  A decision support tool for variant reporting is a relevant approach to harness the next-generation sequencing bioinformatics pipeline output when the complexity of data interpretation exceeds human capabilities.  How can this be accomplished?  What are other use cases? What are the concrete steps for implementation?  In this upcoming webcast, Dr. Joe Lennerz from the Center for Integrated Diagnostics, Massachusetts General Hospital/Harvard Medical School will address these questions.   

Learning Objectives:

  • Recognize the potential of machine learning to facilitate interpretation of genomic data
  • Distinguish 6 necessary components to address a problem using machine learning
  • Compare the relevance of data models vs. flexibility



Speaker
Jochen K. Lennerz, MD, PhD
Moderator
Sabah Kadri, PhD
Duration: 1 hr
Level of Instruction: Basic
Date Recorded: September 10, 2019

Planned and coordinated by the Training and Education Committee

Continuing Education Credit Information

CE Credit for this course has expired.

Note: Members of AMP can access this webinar at no cost. Join the AMP Family!

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