Please note that this content was created in 2018. In the time since this material was posted, there may have been additional developments, advancements, and/or more current publications in this field.
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This is a recording of a session from AMP Europe 2018 meeting in Rotterdam. Purchase the entire AMP Europe 2018 Recordings for a significant discount!
Currently, molecular diagnostic DNA testing is guiding selection of cancer patients who most likely will benefit from targeted treatment (precision medicine). This selection is largely based on the combination of a specific tumor type and the presence or absence of specific mutations in the DNA. Information present in the transcriptome is largely ignored. In this session the clinical importance of similar DNA alterations in different tumor types as well as the use of a combination of both DNA and transcriptomic analyses for drug response prediction will be addressed.
New Insights in the Pathogenesis of MSI Cancers
Aysel Ahadova (Heidelberg, Germany)
Next Generation Pathology Molecular Diagnostics: Combining DNA and RNA Analysis for Treatment
Rene Bernards (Amsterdam, The Netherlands)
Objectives:
- Understand the value of DNA mutation assessment for precision medicine across tumor types.
- Realize the advantages and shortcomings of DNA testing for targeted treatment of cancer.
- Describe how the combination of transcriptome and DNA analysis may improve drug response prediction in cancer patients.
Duration: 1.00 hr
Recording Date: April 30, 2018
Last day to purchase: December 31, 2021
There are no CME/CMLE or SAMs credits available.Note: Join the AMP Family for discounted access to the most current educational resources!
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