Please note that this content was created in 2018. In the time since this material was posted, there may have been additional developments, advancements, and/or more current publications in this field.
AMP Education is constantly updating our educational offerings, and will remove or replace content that is no longer accurate. Please be sure to use the search function to find related or updated material available in our catalogue at educate.amp.org. The Training and Education Committee works with AMP Education Programs to bring you the most up-to-date and cutting-edge information on molecular pathology research, applications, and training.
This is a recording of a session from the AMP 2018 Annual Meeting & Expo. Purchase the entire AMP Annual Meeting & Expo 2018 Recordings for a significant discount!
One of the challenges unanimously faced by clinical laboratories is procuring samples containing the desired types of sequence variant for NGS assay validation and proficiency testing (PT); in particular, uncommon and difficult indels and complex variants. In contrast to physical samples, well-curated and validated in silico sequence data is an invaluable and replenishable resource with many potential clinical use cases. This session will discuss the strength and limitations of in silico sequencing data with insights on current and future clinical application for assay validation and PT.
"In Silico" Proficiency Testing
John D. Pfeifer, MD, PhD, Washington University School of Medicine, St. Louis, MO, USA
In Silico Proficiency Testing for Clinical Next Generation Sequencing
Karl V. Voelkerding, MD, University of Utah School of Medicine, Salt Lake City, UT, USA
Objectives:
- Define in silico sequence datasets and how are they generated, including the tools and software developed for this purpose.
- Describe the strengths and limitations of in silico datasets.
- Discuss the current and future applications of in silico data for assay validation and PT.
Duration: 1.50 hr
Recording Date: November 2, 2018
Last day to purchase: December 31, 2021
There are no CME/CMLE or SAMs credits available.Note: Join the AMP Family for discounted access to the most current educational resources!
All sales are final. No refunds will be issued.
No digital files may be reproduced or transmitted in any form, by any means, electronic or mechanical. By purchasing a product, you agree to not share any of the course materials, including videos, downloadable slide presentations, outlines, manuscripts, etc. without explicit and written permission from AMP.
