Please note that this content was created in 2018. In the time since this material was posted, there may have been additional developments, advancements, and/or more current publications in this field.
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This is a recording of a session from the AMP 2018 Annual Meeting & Expo. Purchase the entire AMP Annual Meeting & Expo 2018 Recordings for a significant discount!
This session will focus on the implementation & validation of a circulating cell free DNA assay for sequence variants, copy number variations, and fusions. The speakers will discuss the clinical indications for ccfDNA testing with an emphasis on the importance of clinical correlation and the pitfalls that may arise when viewing ccfDNA data in isolation. Challenges such as interpretation of somatic versus germline variants as well as interpretation of variants arising in the context of clonal hematopoiesis wil be emphasized.
Clinical Applications of Digital PCR
Maria Arcila, MD, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Liquid Biopsy for Solid Tumors: Promises and Perils
Mark Routbort, MD, PhD, University of Texas MD Anderson Cancer Center, Houston, TX, USA
Objectives:
- Recognize the "cellular compartment of origin" challenge inherent to ccfDNA testing.
- Generate approaches for dealing with likely germline findings of cancer susceptibility.
- Discuss the pre-analytic and standardization challenges associated with ctDNA.
- Summarize the clinical utility of dPCR in ctDNA testing.
Duration: 1.50 hr
Recording Date: November 3, 2018
Last day to purchase: December 31, 2021
There are no CME/CMLE or SAMs credits available.Note: Join the AMP Family for discounted access to the most current educational resources!
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