AMP Annual Meeting Highlights 2016 - CHIPping Away at the Mysteries of Hematopoiesis: The Science and Clinical Implications of Clonal Hematopoiesis of Indeterminate Potential

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Please note that this was recorded in 2016. All AMPEDTM content is reviewed and approved annually by the Training & Education Committee as relevant and accurate, but new data may now be available and new studies may have since been published.

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This is a recording from a session that was presented during the AMP 2016 Annual Meeting in Charlotte, NC.

CHIPping Away at the Mysteries of Hematopoiesis: The Science and Clinical Implications of Clonal Hematopoiesis of Indeterminate Potential

The concept of a pre-cancer clonal proliferation is fundamental to our understanding of the natural evolution of a variety of cancer types and an active area of research. Recent recognition of pre-malignant clonal hematopoiesis has been yet another exciting discovery in this area. The speakers will discuss their work in identifying Clonal Hematopoiesis of Indeterminate Potential (CHIP) and its relationship to both aging and the subsequent development of recognized hematopoietic malignancies.

Learning Objective:

- Explain the concept of clonal hematopoiesis.

- Describe how clonal hematopoiesis can be evaluated using markers identified by high-through sequencing.

- Summarize current knowledge regarding the association between clonal hematopoiesis and the development of recognized hematopoietic cancers, particularly myelodysplastic syndromes.

 

Clonal Hematopoiesis of Indeterminate Potential
Benjamin Ebert, MD, PhD, Brigham and Women's Hospital

CHIP, ICUS, MDS: A Clinical Perspective
David P. Steensma, MD, Dana-Farber Cancer Institute, Boston, MA, USA

Duration1.5 hr

Recording Date: November 10, 2016


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